Novel approaches aim to leap forward cancer research, treatment
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Why cancer treatments become ineffective has long confounded clinicians and is the main reason behind cancer's deadliness. This project will characterize the molecular network that causes this drug resistance. The researchers will focus on two cancers: estrogen-positive breast cancer and melanoma, the most lethal skin cancer. Using quantitative network analysis, they will work to identify networks responsible for drug resistance and explore ways to bypass that resistance at a molecular level. If successful, the theory could likely be used to improve treatments for other cancers that face drug resistance issues.
Jessica Arriens, NSF, (703) 292-2243,
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Guillermo Gonzalo Sánchez Achutegui
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